CAR T-cell Therapy

01 Mar, 2024

Dr. Rajesh Bollam

Using the patient's own immune cells to fight cancer is known as CAR T-cell treatment (Chimeric Antigen Receptor T-cell therapy). It's personalized therapy that includes modifying a patient's T cells, which are immune cells, to improve their ability to identify and destroy cancer cells.

Some advantages of CAR T-cell therapy:

Targeted Treatment:

Because CAR T-cell therapy uses T cells that are particularly designed to recognize and attack cancer cells, it is a highly targeted treatment. This targeted strategy reduces harm to healthy cells.

Highly Effective:

It has been shown that CAR T-cell therapy can be highly successful, particularly in patients with certain blood cancers that have not responded to regular treatments. In certain patients, it has resulted in total remission.

Potential for Long-lasting Response:

CAR T-cell therapy may be able to treat various cancers since it sometimes results in long-lasting remissions.

Clinical Trials:

CAR T-cell therapy is still being studied in clinical trials, which means there is ongoing research to improve its effectiveness and reduce side effects.

Alternative to Traditional Treatments:

CAR T-cell therapy can be a possible option for patients who have not reacted to or are unable to handle previous treatments such as radiation therapy or chemotherapy.

B-cell leukemias and lymphomas are two blood cancer types that have responded remarkably well to CAR T-cell therapy. But it's a complicated and perhaps dangerous procedure that needs careful observation and skilled care. Cytokine release syndrome (CRS) and neurotoxicity are frequent side effects of CAR T-cell therapy. Although they are sometimes severe, they are typically controllable with the right management techniques. Research is still being done to examine the possibility of using CAR T-cell therapy to treat additional forms of cancer in addition to enhancing its efficacy and safety.

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CAR T-cell Therapy

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